{"id":8121,"date":"2018-04-10T15:22:40","date_gmt":"2018-04-10T15:22:40","guid":{"rendered":"https:\/\/capitalpracticeconsulting.com\/dev\/byebyecpap\/?page_id=8121"},"modified":"2020-03-17T15:58:32","modified_gmt":"2020-03-17T15:58:32","slug":"research","status":"publish","type":"page","link":"https:\/\/byebyecpap.com\/research\/","title":{"rendered":"Clinical Research"},"content":{"rendered":"<h1>ORAL APPLIANCE THERAPY FOR TREATMENT OF SLEEP APNEA<\/h1>\n<h2><strong>Clinical studies and Publications on Oral Appliance<\/strong><\/h2>\n<p>There are numerous clinical studies in Oral Appliance Therapy noting the efficacy, compliance and outcome data for oral appliances compared to CPAP. Below are a few of the more recent that may be of interest to you.<\/p>\n<p><strong>New Technology:<\/strong><\/p>\n<ul>\n<li>Determinants of Objective Compliance During Oral Appliance Therapy in Patients With Sleep-Disordered Breathing: A Prospective Clinical Trial. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26402736\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26402736<\/a><\/li>\n<li>Objectively measured vs self-reported compliance during oral appliance therapy for sleep-disordered breathing.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23928873\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23928873<\/a><\/li>\n<\/ul>\n<ul>\n<li>Objective measurement of compliance during oral appliance therapy for sleep-disordered breathing.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22993169\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22993169<\/a><\/li>\n<\/ul>\n<ul>\n<li>Remotely controlled mandibular protrusion during sleep predicts therapeutic success with oral appliances in patients with obstructive sleep apnea.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24082311\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24082311<\/a><\/li>\n<\/ul>\n<ul>\n<li>Prediction of oral appliance treatment outcomes in obstructive sleep apnea: A systematic review.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26773412\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26773412<\/a><\/li>\n<\/ul>\n<ul>\n<li>The Use of Remotely Controlled Mandibular Positioner as a Predictive Screening Tool for Mandibular Advancement Device Therapy in Patients with Obstructive Sleep Apnea through Single-Night Progressive Titration of the Mandible: A Systematic Review.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27568892\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27568892<\/a><\/li>\n<\/ul>\n<p><strong>Review Articles:<\/strong><\/p>\n<ul>\n<li>Mandibular advancement splint (MAS) therapy for obstructive sleep apnoea&#8211;an overview and quality assessment of systematic reviews.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25778946\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25778946<\/a><\/li>\n<\/ul>\n<ul>\n<li>Meta-analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea-hypopnoea.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26163056\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26163056<\/a><\/li>\n<\/ul>\n<ul>\n<li>A crossover randomised controlled trial of oral mandibular advancement devices for obstructive sleep apnoea-hypopnoea (TOMADO).<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25035126\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25035126<\/a><\/li>\n<\/ul>\n<ul>\n<li>Oral appliance treatment for obstructive sleep apnea: an update.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24533007\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24533007<\/a><\/li>\n<\/ul>\n<p><strong>Evidence for Clinical Efficacy\/Patient Preference:<\/strong><\/p>\n<ul>\n<li>Mandibular advancement splint as short-term alternative treatment in patients with obstructive sleep apnea already effectively treated with continuous positive airway pressure.<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23585745\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23585745<\/a><\/li>\n<\/ul>\n<ul>\n<li>Patient preferences and experiences of CPAP and oral appliances for the treatment of obstructive sleep apnea: a qualitative analysis.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22833346\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22833346<\/a><\/li>\n<\/ul>\n<ul>\n<li>Long-term compliance and side effects of oral appliances used for the treatment of snoring and obstructive sleep apnea syndrome.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17561628\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17561628<\/a><\/li>\n<\/ul>\n<ul>\n<li>Dental appliance treatment for obstructive sleep apnea.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17699143\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17699143<\/a><\/li>\n<\/ul>\n<ul>\n<li>Exploring the Potential Cost-Effectiveness of Patient Decision Aids for Use in Adults with Obstructive Sleep Apnea: A Case Study.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25344130\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25344130<\/a><\/li>\n<\/ul>\n<ul>\n<li>Mandibular advancement appliances remain effective in lowering respiratory disturbance index for 2.5-4.5 years.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21925942\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21925942<\/a><\/li>\n<\/ul>\n<ul>\n<li>Mandibular Advancement Device as a Comparable Treatment to Nasal Continuous Positive Airway Pressure for Positional Obstructive Sleep Apnea.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27250814\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27250814<\/a><\/li>\n<\/ul>\n<ul>\n<li>Efficacy versus Effectiveness in the Treatment of Obstructive Sleep Apnea: CPAP and Oral Appliances<br \/>\n<a href=\"http:\/\/www.jdsm.org\/viewarticle.aspx?pid=30229\" target=\"_blank\" rel=\"noopener noreferrer\">http:\/\/www.jdsm.org\/viewarticle.aspx?pid=30229<\/a><\/li>\n<\/ul>\n<ul>\n<li>Effect of jaw-opening exercise on prevention of temporomandibular disorders pain associated with oral appliance therapy in obstructive sleep apnea patients: A randomized, double-blind, placebo-controlled trial<br \/>\n<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1883195816301074\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1883195816301074<\/a><\/li>\n<\/ul>\n<p><strong>Evidence for Improved Clinical Outcomes:<\/strong><\/p>\n<ul>\n<li>Modulation of inflammatory and hemostatic markers in obstructive sleep apnea patients treated with mandibular advancement splints: a parallel, controlled trial.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24634622\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24634622<\/a><\/li>\n<\/ul>\n<ul>\n<li>Health outcomes of continuous positive airway pressure versus oral appliance treatment for obstructive sleep apnea: a randomized controlled trial.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23413266\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23413266<\/a><\/li>\n<\/ul>\n<ul>\n<li>Oral appliance therapy reduces blood pressure in obstructive sleep apnea: a randomized, controlled trial.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15453552\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15453552<\/a><\/li>\n<\/ul>\n<ul>\n<li>Cardiovascular mortality in obstructive sleep apnoea treated with continuous positive airway pressure or oral appliance: an observational study.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23731062\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23731062<\/a><\/li>\n<\/ul>\n<ul>\n<li>Effects of treatment with oral appliance on 24-h blood pressure in patients with obstructive sleep apnea and hypertension: a randomized clinical trial.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22821223\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22821223<\/a><\/li>\n<\/ul>\n<ul>\n<li>Alternatives to continuous positive airway pressure 2: mandibular advancement devices compared.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25221854\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25221854<\/a><\/li>\n<\/ul>\n<ul>\n<li>Mandibular advancement device and CPAP upon cardiovascular parameters in OSA.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24463982\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24463982<\/a><\/li>\n<\/ul>\n<ul>\n<li>Effect of oral appliances on blood pressure in obstructive sleep apnea: a systematic review and meta-analysis.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23372472\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23372472<\/a><\/li>\n<\/ul>\n<ul>\n<li>Effect of oral appliance therapy on neurobehavioral functioning in obstructive sleep apnea: a randomized controlled trial.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17564405\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17564405<\/a><\/li>\n<\/ul>\n<ul>\n<li>Improvement of Cognitive and Psychomotor Performance in Patients with Mild to Moderate Obstructive Sleep Apnea Treated with Mandibular Advancement Device: A Prospective 1-Year Study.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26414974\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26414974<\/a><\/li>\n<\/ul>\n<ul>\n<li>CPAP vs Mandibular Advancement Devices and Blood Pressure in Patients With Obstructive Sleep Apnea: A Systematic Review and Meta-analysis.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26624827\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26624827<\/a><\/li>\n<\/ul>\n<ul>\n<li>Comparison of effects of OSA treatment by MAD and by CPAP on cardiac autonomic function during daytime.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26463420\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26463420<\/a><\/li>\n<\/ul>\n<ul>\n<li>Oral appliance treatment for obstructive sleep apnea: an update.<br \/>\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24533007\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24533007<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>ORAL APPLIANCE THERAPY FOR TREATMENT OF SLEEP APNEA Clinical studies and Publications on Oral Appliance There are numerous clinical studies in Oral Appliance Therapy noting the efficacy, compliance and outcome data for oral appliances compared to CPAP. Below are a few of the more recent that may be of interest to you. New Technology: Determinants&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-8121","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Oral Appliance Therapy for Sleep Apnea | Clinical Research | VA, MD, DC area<\/title>\n<meta name=\"description\" content=\"Clinical Research on the effetiveness of Oral Appliance Therapy for the treatment of Sleep Apnea | Washington DC Metro Area\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/byebyecpap.com\/research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Oral 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