ORAL APPLIANCE THERAPY FOR TREATMENT OF SLEEP APNEA
Clinical studies and Publications on Oral Appliance
There are numerous clinical studies in Oral Appliance Therapy noting the efficacy, compliance and outcome data for oral appliances compared to CPAP. Below are a few of the more recent that may be of interest to you.
New Technology:
- Determinants of Objective Compliance During Oral Appliance Therapy in Patients With Sleep-Disordered Breathing: A Prospective Clinical Trial. https://www.ncbi.nlm.nih.gov/pubmed/26402736
- Objectively measured vs self-reported compliance during oral appliance therapy for sleep-disordered breathing.
https://www.ncbi.nlm.nih.gov/pubmed/23928873
- Objective measurement of compliance during oral appliance therapy for sleep-disordered breathing.
https://www.ncbi.nlm.nih.gov/pubmed/22993169
- Remotely controlled mandibular protrusion during sleep predicts therapeutic success with oral appliances in patients with obstructive sleep apnea.
https://www.ncbi.nlm.nih.gov/pubmed/24082311
- Prediction of oral appliance treatment outcomes in obstructive sleep apnea: A systematic review.
https://www.ncbi.nlm.nih.gov/pubmed/26773412
- The Use of Remotely Controlled Mandibular Positioner as a Predictive Screening Tool for Mandibular Advancement Device Therapy in Patients with Obstructive Sleep Apnea through Single-Night Progressive Titration of the Mandible: A Systematic Review.
https://www.ncbi.nlm.nih.gov/pubmed/27568892
Review Articles:
- Mandibular advancement splint (MAS) therapy for obstructive sleep apnoea–an overview and quality assessment of systematic reviews.
https://www.ncbi.nlm.nih.gov/pubmed/25778946
- Meta-analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea-hypopnoea.
https://www.ncbi.nlm.nih.gov/pubmed/26163056
- A crossover randomised controlled trial of oral mandibular advancement devices for obstructive sleep apnoea-hypopnoea (TOMADO).
https://www.ncbi.nlm.nih.gov/pubmed/25035126
- Oral appliance treatment for obstructive sleep apnea: an update.
https://www.ncbi.nlm.nih.gov/pubmed/24533007
Evidence for Clinical Efficacy/Patient Preference:
- Mandibular advancement splint as short-term alternative treatment in patients with obstructive sleep apnea already effectively treated with continuous positive airway pressure.https://www.ncbi.nlm.nih.gov/pubmed/23585745
- Patient preferences and experiences of CPAP and oral appliances for the treatment of obstructive sleep apnea: a qualitative analysis.
https://www.ncbi.nlm.nih.gov/pubmed/22833346
- Long-term compliance and side effects of oral appliances used for the treatment of snoring and obstructive sleep apnea syndrome.
https://www.ncbi.nlm.nih.gov/pubmed/17561628
- Dental appliance treatment for obstructive sleep apnea.
https://www.ncbi.nlm.nih.gov/pubmed/17699143
- Exploring the Potential Cost-Effectiveness of Patient Decision Aids for Use in Adults with Obstructive Sleep Apnea: A Case Study.
https://www.ncbi.nlm.nih.gov/pubmed/25344130
- Mandibular advancement appliances remain effective in lowering respiratory disturbance index for 2.5-4.5 years.
https://www.ncbi.nlm.nih.gov/pubmed/21925942
- Mandibular Advancement Device as a Comparable Treatment to Nasal Continuous Positive Airway Pressure for Positional Obstructive Sleep Apnea.
https://www.ncbi.nlm.nih.gov/pubmed/27250814
- Efficacy versus Effectiveness in the Treatment of Obstructive Sleep Apnea: CPAP and Oral Appliances
http://www.jdsm.org/viewarticle.aspx?pid=30229
- Effect of jaw-opening exercise on prevention of temporomandibular disorders pain associated with oral appliance therapy in obstructive sleep apnea patients: A randomized, double-blind, placebo-controlled trial
https://www.sciencedirect.com/science/article/pii/S1883195816301074
Evidence for Improved Clinical Outcomes:
- Modulation of inflammatory and hemostatic markers in obstructive sleep apnea patients treated with mandibular advancement splints: a parallel, controlled trial.
https://www.ncbi.nlm.nih.gov/pubmed/24634622
- Health outcomes of continuous positive airway pressure versus oral appliance treatment for obstructive sleep apnea: a randomized controlled trial.
https://www.ncbi.nlm.nih.gov/pubmed/23413266
- Oral appliance therapy reduces blood pressure in obstructive sleep apnea: a randomized, controlled trial.
https://www.ncbi.nlm.nih.gov/pubmed/15453552
- Cardiovascular mortality in obstructive sleep apnoea treated with continuous positive airway pressure or oral appliance: an observational study.
https://www.ncbi.nlm.nih.gov/pubmed/23731062
- Effects of treatment with oral appliance on 24-h blood pressure in patients with obstructive sleep apnea and hypertension: a randomized clinical trial.
https://www.ncbi.nlm.nih.gov/pubmed/22821223
- Alternatives to continuous positive airway pressure 2: mandibular advancement devices compared.
https://www.ncbi.nlm.nih.gov/pubmed/25221854
- Mandibular advancement device and CPAP upon cardiovascular parameters in OSA.
https://www.ncbi.nlm.nih.gov/pubmed/24463982
- Effect of oral appliances on blood pressure in obstructive sleep apnea: a systematic review and meta-analysis.
https://www.ncbi.nlm.nih.gov/pubmed/23372472
- Effect of oral appliance therapy on neurobehavioral functioning in obstructive sleep apnea: a randomized controlled trial.
https://www.ncbi.nlm.nih.gov/pubmed/17564405
- Improvement of Cognitive and Psychomotor Performance in Patients with Mild to Moderate Obstructive Sleep Apnea Treated with Mandibular Advancement Device: A Prospective 1-Year Study.
https://www.ncbi.nlm.nih.gov/pubmed/26414974
- CPAP vs Mandibular Advancement Devices and Blood Pressure in Patients With Obstructive Sleep Apnea: A Systematic Review and Meta-analysis.
https://www.ncbi.nlm.nih.gov/pubmed/26624827
- Comparison of effects of OSA treatment by MAD and by CPAP on cardiac autonomic function during daytime.
https://www.ncbi.nlm.nih.gov/pubmed/26463420
- Oral appliance treatment for obstructive sleep apnea: an update.
https://www.ncbi.nlm.nih.gov/pubmed/24533007